The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia

The nature of the immunoglobulin (Ig) G found associated with the neoplastic B lymphocytes in chronic lymphocytic leukemia that also express Igm and IgD had been investigated by absorption studies using anti-idiotypic antibodies raised against cell surface IgM from five patients. In all five cases,...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186541/
https://www.ncbi.nlm.nih.gov/pubmed/6976409
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description The nature of the immunoglobulin (Ig) G found associated with the neoplastic B lymphocytes in chronic lymphocytic leukemia that also express Igm and IgD had been investigated by absorption studies using anti-idiotypic antibodies raised against cell surface IgM from five patients. In all five cases, although cellular IgM and IgD behaved as idiotypic, the IgG did not. Thus the IgG frequently found associated with lymphocytes at this stage of differentiation is likely, at least in many cases, to be of extrinsic origin.
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spelling pubmed-21865412008-04-17 The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia J Exp Med Articles The nature of the immunoglobulin (Ig) G found associated with the neoplastic B lymphocytes in chronic lymphocytic leukemia that also express Igm and IgD had been investigated by absorption studies using anti-idiotypic antibodies raised against cell surface IgM from five patients. In all five cases, although cellular IgM and IgD behaved as idiotypic, the IgG did not. Thus the IgG frequently found associated with lymphocytes at this stage of differentiation is likely, at least in many cases, to be of extrinsic origin. The Rockefeller University Press 1981-12-01 /pmc/articles/PMC2186541/ /pubmed/6976409 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia
title The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia
title_full The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia
title_fullStr The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia
title_full_unstemmed The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia
title_short The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia
title_sort nature of the immunoglobulin g on the surface of b lymphocytes in chronic lymphocytic leukemia
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186541/
https://www.ncbi.nlm.nih.gov/pubmed/6976409

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