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T cell clones with dual specificity for M1s and various major histocompatibility complex determinants

A high proportion of T cell clones derived from bulk cultures selected to M1s a,d determinants were found to have joint specificity for allo-H- 2 determinants, and vice versa. Significantly, the patterns of H-2 alloreactivity shown by clones selected to M1sa,b determinants appeared to be random. The...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186545/
https://www.ncbi.nlm.nih.gov/pubmed/6172537
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description A high proportion of T cell clones derived from bulk cultures selected to M1s a,d determinants were found to have joint specificity for allo-H- 2 determinants, and vice versa. Significantly, the patterns of H-2 alloreactivity shown by clones selected to M1sa,b determinants appeared to be random. The possible implications of these findings are discussed.
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spelling pubmed-21865452008-04-17 T cell clones with dual specificity for M1s and various major histocompatibility complex determinants J Exp Med Articles A high proportion of T cell clones derived from bulk cultures selected to M1s a,d determinants were found to have joint specificity for allo-H- 2 determinants, and vice versa. Significantly, the patterns of H-2 alloreactivity shown by clones selected to M1sa,b determinants appeared to be random. The possible implications of these findings are discussed. The Rockefeller University Press 1981-12-01 /pmc/articles/PMC2186545/ /pubmed/6172537 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
T cell clones with dual specificity for M1s and various major histocompatibility complex determinants
title T cell clones with dual specificity for M1s and various major histocompatibility complex determinants
title_full T cell clones with dual specificity for M1s and various major histocompatibility complex determinants
title_fullStr T cell clones with dual specificity for M1s and various major histocompatibility complex determinants
title_full_unstemmed T cell clones with dual specificity for M1s and various major histocompatibility complex determinants
title_short T cell clones with dual specificity for M1s and various major histocompatibility complex determinants
title_sort t cell clones with dual specificity for m1s and various major histocompatibility complex determinants
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186545/
https://www.ncbi.nlm.nih.gov/pubmed/6172537