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Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding prote...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1982
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186592/ https://www.ncbi.nlm.nih.gov/pubmed/6977010 |
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collection | PubMed |
description | A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding protein has a 62,000 mol wt, and, when analyzed by direct binding, the molecule reacts with several different rabbit anti- idiotypic antisera specific to the ABA system. The presence of this antigen-specific, "idiotype positive" molecule in many different cells indicates that it is not an important immunoregulatory molecule. |
format | Text |
id | pubmed-2186592 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1982 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21865922008-04-17 Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells J Exp Med Articles A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding protein has a 62,000 mol wt, and, when analyzed by direct binding, the molecule reacts with several different rabbit anti- idiotypic antisera specific to the ABA system. The presence of this antigen-specific, "idiotype positive" molecule in many different cells indicates that it is not an important immunoregulatory molecule. The Rockefeller University Press 1982-02-01 /pmc/articles/PMC2186592/ /pubmed/6977010 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
title | Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
title_full | Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
title_fullStr | Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
title_full_unstemmed | Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
title_short | Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
title_sort | ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186592/ https://www.ncbi.nlm.nih.gov/pubmed/6977010 |