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Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells

A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding prote...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186592/
https://www.ncbi.nlm.nih.gov/pubmed/6977010
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description A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding protein has a 62,000 mol wt, and, when analyzed by direct binding, the molecule reacts with several different rabbit anti- idiotypic antisera specific to the ABA system. The presence of this antigen-specific, "idiotype positive" molecule in many different cells indicates that it is not an important immunoregulatory molecule.
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spelling pubmed-21865922008-04-17 Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells J Exp Med Articles A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding protein has a 62,000 mol wt, and, when analyzed by direct binding, the molecule reacts with several different rabbit anti- idiotypic antisera specific to the ABA system. The presence of this antigen-specific, "idiotype positive" molecule in many different cells indicates that it is not an important immunoregulatory molecule. The Rockefeller University Press 1982-02-01 /pmc/articles/PMC2186592/ /pubmed/6977010 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
title Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
title_full Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
title_fullStr Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
title_full_unstemmed Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
title_short Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
title_sort ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186592/
https://www.ncbi.nlm.nih.gov/pubmed/6977010