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Inducible expression of insulin receptors on T lymphocyte clones
This study demonstrates that the insulin receptors are expressed on the surface of some T cell clones after specific antigenic stimulation. The insulin receptors on these lymphocytes are physicochemically similar to insulin receptors present on cells which express the receptors constitutively (adipo...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1982
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186756/ https://www.ncbi.nlm.nih.gov/pubmed/7047673 |
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collection | PubMed |
description | This study demonstrates that the insulin receptors are expressed on the surface of some T cell clones after specific antigenic stimulation. The insulin receptors on these lymphocytes are physicochemically similar to insulin receptors present on cells which express the receptors constitutively (adipocytes, hepatocytes, etc.). The kinetics of expression of insulin receptors on cloned, noncytotoxic T cells after specific antigenic stimulation closely parallels that of [3H]thymidine incorporation in such cultures. |
format | Text |
id | pubmed-2186756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1982 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21867562008-04-17 Inducible expression of insulin receptors on T lymphocyte clones J Exp Med Articles This study demonstrates that the insulin receptors are expressed on the surface of some T cell clones after specific antigenic stimulation. The insulin receptors on these lymphocytes are physicochemically similar to insulin receptors present on cells which express the receptors constitutively (adipocytes, hepatocytes, etc.). The kinetics of expression of insulin receptors on cloned, noncytotoxic T cells after specific antigenic stimulation closely parallels that of [3H]thymidine incorporation in such cultures. The Rockefeller University Press 1982-08-01 /pmc/articles/PMC2186756/ /pubmed/7047673 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Inducible expression of insulin receptors on T lymphocyte clones |
title | Inducible expression of insulin receptors on T lymphocyte clones |
title_full | Inducible expression of insulin receptors on T lymphocyte clones |
title_fullStr | Inducible expression of insulin receptors on T lymphocyte clones |
title_full_unstemmed | Inducible expression of insulin receptors on T lymphocyte clones |
title_short | Inducible expression of insulin receptors on T lymphocyte clones |
title_sort | inducible expression of insulin receptors on t lymphocyte clones |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186756/ https://www.ncbi.nlm.nih.gov/pubmed/7047673 |