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Generation of cytolytic T lymphocytes in thymectomized, irradiated, and bone marrow-reconstituted mice
A model system has been developed to study extrathymic T cell differentiation. Mice have been thymectomized, lethally irradiated, and reconstituted with bone marrow cells depleted of Thy-1-positive cells. After 8 wk, the spleen cells of these 5athymic, bone marrow- reconstituted chimeras contain Thy...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1982
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186799/ https://www.ncbi.nlm.nih.gov/pubmed/6125557 |