Multiple human beta interferon genes

Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translati...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1982
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186800/
https://www.ncbi.nlm.nih.gov/pubmed/6180119
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collection PubMed
description Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. The results obtained are consistent with the existence of IFN-beta genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed.
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spelling pubmed-21868002008-04-17 Multiple human beta interferon genes J Exp Med Articles Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. The results obtained are consistent with the existence of IFN-beta genes on different human chromosomes. Marked cell-dependent variability in the expression of these IFN mRNA species was observed. The Rockefeller University Press 1982-09-01 /pmc/articles/PMC2186800/ /pubmed/6180119 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Multiple human beta interferon genes
title Multiple human beta interferon genes
title_full Multiple human beta interferon genes
title_fullStr Multiple human beta interferon genes
title_full_unstemmed Multiple human beta interferon genes
title_short Multiple human beta interferon genes
title_sort multiple human beta interferon genes
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186800/
https://www.ncbi.nlm.nih.gov/pubmed/6180119

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