Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets

The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma. Antigenic markers that distinguish early, intermediate, and mature stages in melanocyte differentiation have been defined. The characte...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1982
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186870/
https://www.ncbi.nlm.nih.gov/pubmed/7175440
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description The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma. Antigenic markers that distinguish early, intermediate, and mature stages in melanocyte differentiation have been defined. The characteristics of the normal melanocyte precursor have been inferred from the features of melanomas that express early markers of melanocyte differentiation. A rudimentary surface antigen map of cells undergoing melanocyte differentiation and a new classification of melanomas based on the expression of melanocyte differentiation antigens are proposed.
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spelling pubmed-21868702008-04-17 Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets J Exp Med Articles The surface antigens of melanocytes from newborn and adult skin have been analyzed with monoclonal antibodies detecting cell surface antigens of malignant melanoma. Antigenic markers that distinguish early, intermediate, and mature stages in melanocyte differentiation have been defined. The characteristics of the normal melanocyte precursor have been inferred from the features of melanomas that express early markers of melanocyte differentiation. A rudimentary surface antigen map of cells undergoing melanocyte differentiation and a new classification of melanomas based on the expression of melanocyte differentiation antigens are proposed. The Rockefeller University Press 1982-12-01 /pmc/articles/PMC2186870/ /pubmed/7175440 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
title Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
title_full Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
title_fullStr Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
title_full_unstemmed Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
title_short Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
title_sort surface antigens of melanocytes and melanomas. markers of melanocyte differentiation and melanoma subsets
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186870/
https://www.ncbi.nlm.nih.gov/pubmed/7175440

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