Helper cell-independent cytotoxic clones in man

We report here a class of helper cell-independent cytotoxic T cell (HITc) clones in man that can proliferate in response to antigenic stimulation as well as mediate cytotoxicity. HITc appear to be rare among clones derived from primary in vitro allosensitized culture, but constitute the majority of...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1982
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186881/
https://www.ncbi.nlm.nih.gov/pubmed/6217275
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description We report here a class of helper cell-independent cytotoxic T cell (HITc) clones in man that can proliferate in response to antigenic stimulation as well as mediate cytotoxicity. HITc appear to be rare among clones derived from primary in vitro allosensitized culture, but constitute the majority of clones derived from cells sensitized to autologous Epstein-Barr virus-transformed lymphoblastoid cell lines. The implications of the derivation and function of HITc clones are discussed.
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spelling pubmed-21868812008-04-17 Helper cell-independent cytotoxic clones in man J Exp Med Articles We report here a class of helper cell-independent cytotoxic T cell (HITc) clones in man that can proliferate in response to antigenic stimulation as well as mediate cytotoxicity. HITc appear to be rare among clones derived from primary in vitro allosensitized culture, but constitute the majority of clones derived from cells sensitized to autologous Epstein-Barr virus-transformed lymphoblastoid cell lines. The implications of the derivation and function of HITc clones are discussed. The Rockefeller University Press 1982-12-01 /pmc/articles/PMC2186881/ /pubmed/6217275 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Helper cell-independent cytotoxic clones in man
title Helper cell-independent cytotoxic clones in man
title_full Helper cell-independent cytotoxic clones in man
title_fullStr Helper cell-independent cytotoxic clones in man
title_full_unstemmed Helper cell-independent cytotoxic clones in man
title_short Helper cell-independent cytotoxic clones in man
title_sort helper cell-independent cytotoxic clones in man
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186881/
https://www.ncbi.nlm.nih.gov/pubmed/6217275

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