Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth

The attributes of the test grafts with which putatively tolerant rats are challenged influence their immune response. Lewis (Lew) rats inoculated at birth with Lew/BN F1 hybrid bone marrow cells accept large skin allografts more readily than small allografts, and F1 hybrid skin grafts survive better...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186937/
https://www.ncbi.nlm.nih.gov/pubmed/6337230
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collection PubMed
description The attributes of the test grafts with which putatively tolerant rats are challenged influence their immune response. Lewis (Lew) rats inoculated at birth with Lew/BN F1 hybrid bone marrow cells accept large skin allografts more readily than small allografts, and F1 hybrid skin grafts survive better than BN transplants. The results indicate that the survivals of these major histocompatibility complex- incompatible grafts are determined by the same factors that operate when only weak histoincompatibilities prevail.
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spelling pubmed-21869372008-04-17 Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth J Exp Med Articles The attributes of the test grafts with which putatively tolerant rats are challenged influence their immune response. Lewis (Lew) rats inoculated at birth with Lew/BN F1 hybrid bone marrow cells accept large skin allografts more readily than small allografts, and F1 hybrid skin grafts survive better than BN transplants. The results indicate that the survivals of these major histocompatibility complex- incompatible grafts are determined by the same factors that operate when only weak histoincompatibilities prevail. The Rockefeller University Press 1983-02-01 /pmc/articles/PMC2186937/ /pubmed/6337230 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
title Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
title_full Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
title_fullStr Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
title_full_unstemmed Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
title_short Influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
title_sort influence of size and gene dosage on the survival of skin allografts on rats rendered tolerant at birth
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186937/
https://www.ncbi.nlm.nih.gov/pubmed/6337230

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