Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen

Monoclonal antibodies J5, VIL-A1, and BA-3, known to react with the common acute lymphoblastic leukemia antigen (CALLA) were found to specifically stain normal human polymorphonuclear neutrophils (PMN). The antigen detected on PMN had a molecular weight (95,000-110,000 mol wt) close to that of CALLA...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186955/
https://www.ncbi.nlm.nih.gov/pubmed/6220104
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collection PubMed
description Monoclonal antibodies J5, VIL-A1, and BA-3, known to react with the common acute lymphoblastic leukemia antigen (CALLA) were found to specifically stain normal human polymorphonuclear neutrophils (PMN). The antigen detected on PMN had a molecular weight (95,000-110,000 mol wt) close to that of CALLA (95,000-100,000 mol wt) and thus these surface membrane antigens are likely related, if not identical. The fluorescent staining intensity of PMN is comparable to that of CALLA- positive leukemic cells and the presence of PMN in patient samples could potentially produce false-positive results in diagnosis.
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spelling pubmed-21869552008-04-17 Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen J Exp Med Articles Monoclonal antibodies J5, VIL-A1, and BA-3, known to react with the common acute lymphoblastic leukemia antigen (CALLA) were found to specifically stain normal human polymorphonuclear neutrophils (PMN). The antigen detected on PMN had a molecular weight (95,000-110,000 mol wt) close to that of CALLA (95,000-100,000 mol wt) and thus these surface membrane antigens are likely related, if not identical. The fluorescent staining intensity of PMN is comparable to that of CALLA- positive leukemic cells and the presence of PMN in patient samples could potentially produce false-positive results in diagnosis. The Rockefeller University Press 1983-03-01 /pmc/articles/PMC2186955/ /pubmed/6220104 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
title Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
title_full Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
title_fullStr Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
title_full_unstemmed Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
title_short Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
title_sort polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186955/
https://www.ncbi.nlm.nih.gov/pubmed/6220104

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