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Immune human lymphocytes produce an acid-labile α-interferon
We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune diseas...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1983
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186960/ https://www.ncbi.nlm.nih.gov/pubmed/6403647 |
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author | Balkwill, FR Griffin, DB Band, HA Beverley, PCL |
author_facet | Balkwill, FR Griffin, DB Band, HA Beverley, PCL |
author_sort | Balkwill, FR |
collection | PubMed |
description | We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune disease (10). The system described here will be useful in elucidating the biological significance and cell of origin of this IFN. |
format | Text |
id | pubmed-2186960 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1983 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21869602008-04-17 Immune human lymphocytes produce an acid-labile α-interferon Balkwill, FR Griffin, DB Band, HA Beverley, PCL J Exp Med Articles We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune disease (10). The system described here will be useful in elucidating the biological significance and cell of origin of this IFN. The Rockefeller University Press 1983-03-01 /pmc/articles/PMC2186960/ /pubmed/6403647 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Balkwill, FR Griffin, DB Band, HA Beverley, PCL Immune human lymphocytes produce an acid-labile α-interferon |
title | Immune human lymphocytes produce an acid-labile α-interferon |
title_full | Immune human lymphocytes produce an acid-labile α-interferon |
title_fullStr | Immune human lymphocytes produce an acid-labile α-interferon |
title_full_unstemmed | Immune human lymphocytes produce an acid-labile α-interferon |
title_short | Immune human lymphocytes produce an acid-labile α-interferon |
title_sort | immune human lymphocytes produce an acid-labile α-interferon |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186960/ https://www.ncbi.nlm.nih.gov/pubmed/6403647 |
work_keys_str_mv | AT balkwillfr immunehumanlymphocytesproduceanacidlabileainterferon AT griffindb immunehumanlymphocytesproduceanacidlabileainterferon AT bandha immunehumanlymphocytesproduceanacidlabileainterferon AT beverleypcl immunehumanlymphocytesproduceanacidlabileainterferon |