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Immune human lymphocytes produce an acid-labile α-interferon

We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune diseas...

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Detalles Bibliográficos
Autores principales: Balkwill, FR, Griffin, DB, Band, HA, Beverley, PCL
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186960/
https://www.ncbi.nlm.nih.gov/pubmed/6403647
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author Balkwill, FR
Griffin, DB
Band, HA
Beverley, PCL
author_facet Balkwill, FR
Griffin, DB
Band, HA
Beverley, PCL
author_sort Balkwill, FR
collection PubMed
description We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune disease (10). The system described here will be useful in elucidating the biological significance and cell of origin of this IFN.
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spelling pubmed-21869602008-04-17 Immune human lymphocytes produce an acid-labile α-interferon Balkwill, FR Griffin, DB Band, HA Beverley, PCL J Exp Med Articles We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune disease (10). The system described here will be useful in elucidating the biological significance and cell of origin of this IFN. The Rockefeller University Press 1983-03-01 /pmc/articles/PMC2186960/ /pubmed/6403647 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Balkwill, FR
Griffin, DB
Band, HA
Beverley, PCL
Immune human lymphocytes produce an acid-labile α-interferon
title Immune human lymphocytes produce an acid-labile α-interferon
title_full Immune human lymphocytes produce an acid-labile α-interferon
title_fullStr Immune human lymphocytes produce an acid-labile α-interferon
title_full_unstemmed Immune human lymphocytes produce an acid-labile α-interferon
title_short Immune human lymphocytes produce an acid-labile α-interferon
title_sort immune human lymphocytes produce an acid-labile α-interferon
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186960/
https://www.ncbi.nlm.nih.gov/pubmed/6403647
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