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Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2
Spleen cells derived from aged (30 mo) C57Bl/6 mice are shown to be deficient in the ability to generate suppressor cell activity in vitro. The addition of IL-2 to cultures containing aged cells restores this function to a large extent.
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1983
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187056/ https://www.ncbi.nlm.nih.gov/pubmed/6222139 |
| _version_ | 1782146085800640512 |
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| collection | PubMed |
| description | Spleen cells derived from aged (30 mo) C57Bl/6 mice are shown to be deficient in the ability to generate suppressor cell activity in vitro. The addition of IL-2 to cultures containing aged cells restores this function to a large extent. |
| format | Text |
| id | pubmed-2187056 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1983 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21870562008-04-17 Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 J Exp Med Articles Spleen cells derived from aged (30 mo) C57Bl/6 mice are shown to be deficient in the ability to generate suppressor cell activity in vitro. The addition of IL-2 to cultures containing aged cells restores this function to a large extent. The Rockefeller University Press 1983-06-01 /pmc/articles/PMC2187056/ /pubmed/6222139 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Articles Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 |
| title | Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 |
| title_full | Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 |
| title_fullStr | Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 |
| title_full_unstemmed | Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 |
| title_short | Deficiency in suppressor T cell activity in aged animals. Reconstitution of this activity by interleukin 2 |
| title_sort | deficiency in suppressor t cell activity in aged animals. reconstitution of this activity by interleukin 2 |
| topic | Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187056/ https://www.ncbi.nlm.nih.gov/pubmed/6222139 |