Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution

Lethally irradiated rats treated with cyclosporin A (CsA) for 20-40 d develop classic graft-versus-host disease (GVHD) when reconstituted with syngeneic or autologous bone marrow, upon discontinuation of CsA, whereas normal rats do not. Syngeneic GVHD may be transferred to irradiated but not normal...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187068/
https://www.ncbi.nlm.nih.gov/pubmed/6345713
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description Lethally irradiated rats treated with cyclosporin A (CsA) for 20-40 d develop classic graft-versus-host disease (GVHD) when reconstituted with syngeneic or autologous bone marrow, upon discontinuation of CsA, whereas normal rats do not. Syngeneic GVHD may be transferred to irradiated but not normal syngeneic recipients. Normal spleen cells fail to prevent the development or adoptive transfer of syngeneic GVHD.
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spelling pubmed-21870682008-04-17 Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution J Exp Med Articles Lethally irradiated rats treated with cyclosporin A (CsA) for 20-40 d develop classic graft-versus-host disease (GVHD) when reconstituted with syngeneic or autologous bone marrow, upon discontinuation of CsA, whereas normal rats do not. Syngeneic GVHD may be transferred to irradiated but not normal syngeneic recipients. Normal spleen cells fail to prevent the development or adoptive transfer of syngeneic GVHD. The Rockefeller University Press 1983-07-01 /pmc/articles/PMC2187068/ /pubmed/6345713 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
title Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
title_full Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
title_fullStr Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
title_full_unstemmed Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
title_short Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution
title_sort graft-versus-host disease in cyclosporin a-treated rats after syngeneic and autologous bone marrow reconstitution
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187068/
https://www.ncbi.nlm.nih.gov/pubmed/6345713

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