Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas

In the presence of the soluble polypeptide antigens ovalbumin and keyhole limpet hemocyanin, purified mouse spleen dendritic cells induce the secretion of IL-2 by antigen-specific T cell hybridomas. This response is H-2 restricted and can be specifically inhibited by monoclonal anti-I-A. These data...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187132/
https://www.ncbi.nlm.nih.gov/pubmed/6605410
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collection PubMed
description In the presence of the soluble polypeptide antigens ovalbumin and keyhole limpet hemocyanin, purified mouse spleen dendritic cells induce the secretion of IL-2 by antigen-specific T cell hybridomas. This response is H-2 restricted and can be specifically inhibited by monoclonal anti-I-A. These data indicate that dendritic cells can present soluble antigen to H-2-compatible T cells.
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spelling pubmed-21871322008-04-17 Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas J Exp Med Articles In the presence of the soluble polypeptide antigens ovalbumin and keyhole limpet hemocyanin, purified mouse spleen dendritic cells induce the secretion of IL-2 by antigen-specific T cell hybridomas. This response is H-2 restricted and can be specifically inhibited by monoclonal anti-I-A. These data indicate that dendritic cells can present soluble antigen to H-2-compatible T cells. The Rockefeller University Press 1983-11-01 /pmc/articles/PMC2187132/ /pubmed/6605410 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas
title Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas
title_full Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas
title_fullStr Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas
title_full_unstemmed Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas
title_short Mouse spleen dendritic cells present soluble antigens to antigen- specific T cell hybridomas
title_sort mouse spleen dendritic cells present soluble antigens to antigen- specific t cell hybridomas
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187132/
https://www.ncbi.nlm.nih.gov/pubmed/6605410

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