The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors

Human alloreactive proliferating T cell clones have been compared for their capacity to provide help for B cell activation and the generation of a specific cytotoxic response. The results demonstrate that, when triggered by the relevant alloantigen, the same T cell clone can induce a strong polyclon...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1984
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187196/
https://www.ncbi.nlm.nih.gov/pubmed/6229595
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description Human alloreactive proliferating T cell clones have been compared for their capacity to provide help for B cell activation and the generation of a specific cytotoxic response. The results demonstrate that, when triggered by the relevant alloantigen, the same T cell clone can induce a strong polyclonal B cell activation and serve as the only source of helper cells for the generation of a specific cytotoxic response by any source of CTL precursors against any stimulator cell present in culture.
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spelling pubmed-21871962008-04-17 The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors J Exp Med Articles Human alloreactive proliferating T cell clones have been compared for their capacity to provide help for B cell activation and the generation of a specific cytotoxic response. The results demonstrate that, when triggered by the relevant alloantigen, the same T cell clone can induce a strong polyclonal B cell activation and serve as the only source of helper cells for the generation of a specific cytotoxic response by any source of CTL precursors against any stimulator cell present in culture. The Rockefeller University Press 1984-01-01 /pmc/articles/PMC2187196/ /pubmed/6229595 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
title The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
title_full The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
title_fullStr The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
title_full_unstemmed The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
title_short The same human alloreactive T cell clone can help both B lymphocytes and specific cytotoxic precursors
title_sort same human alloreactive t cell clone can help both b lymphocytes and specific cytotoxic precursors
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187196/
https://www.ncbi.nlm.nih.gov/pubmed/6229595

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