Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice

The homologous, monoclonal antiidiotope, MB, induced idiotope suppression that was remarkably stable and could be transferred by B lymphocytes. Marked depletion of T cell function, confirmed by limiting diluting analysis, did not affect the ability of MB to suppress the corresponding idiotope. Suppr...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1984
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187275/
https://www.ncbi.nlm.nih.gov/pubmed/6608575
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description The homologous, monoclonal antiidiotope, MB, induced idiotope suppression that was remarkably stable and could be transferred by B lymphocytes. Marked depletion of T cell function, confirmed by limiting diluting analysis, did not affect the ability of MB to suppress the corresponding idiotope. Suppression induced by MB appears to result from direct interaction with idiotope-positive B cells, without the intervention of idiotope-specific T suppressor cells.
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spelling pubmed-21872752008-04-17 Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice J Exp Med Articles The homologous, monoclonal antiidiotope, MB, induced idiotope suppression that was remarkably stable and could be transferred by B lymphocytes. Marked depletion of T cell function, confirmed by limiting diluting analysis, did not affect the ability of MB to suppress the corresponding idiotope. Suppression induced by MB appears to result from direct interaction with idiotope-positive B cells, without the intervention of idiotope-specific T suppressor cells. The Rockefeller University Press 1984-04-01 /pmc/articles/PMC2187275/ /pubmed/6608575 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice
title Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice
title_full Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice
title_fullStr Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice
title_full_unstemmed Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice
title_short Induction of idiotope suppression in the anti-azophenylarsonate response of T-depleted A/J mice
title_sort induction of idiotope suppression in the anti-azophenylarsonate response of t-depleted a/j mice
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187275/
https://www.ncbi.nlm.nih.gov/pubmed/6608575

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