A new gene that controls the type of leukemia induced by Friend murine leukemia virus

NB tropic Friend murine leukemia virus (F-MuLV) replicates equally well in BALB/c and C57BL mice inoculated as neonates but causes almost exclusively erythroblastosis in BALB/c mice and nonerythroid (lymphoid and myelogenous) leukemias in C57BL mice. The C57BL resistance to erythroblastosis appears...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1983
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187339/
https://www.ncbi.nlm.nih.gov/pubmed/6577128
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collection PubMed
description NB tropic Friend murine leukemia virus (F-MuLV) replicates equally well in BALB/c and C57BL mice inoculated as neonates but causes almost exclusively erythroblastosis in BALB/c mice and nonerythroid (lymphoid and myelogenous) leukemias in C57BL mice. The C57BL resistance to erythroblastosis appears to be controlled by a single dominant gene in first and second backcrosses to BALB/c. This resistance to erythroblastosis is distinct from other genes known to affect susceptibility to Friend virus including Fv-1, Fv-2, H-2, Rfv-3, Fv-4, and Rmcf. We suggest the name Fhe for the new gene controlling susceptibility to Friend helper virus erythroblastosis.
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spelling pubmed-21873392008-04-17 A new gene that controls the type of leukemia induced by Friend murine leukemia virus J Exp Med Articles NB tropic Friend murine leukemia virus (F-MuLV) replicates equally well in BALB/c and C57BL mice inoculated as neonates but causes almost exclusively erythroblastosis in BALB/c mice and nonerythroid (lymphoid and myelogenous) leukemias in C57BL mice. The C57BL resistance to erythroblastosis appears to be controlled by a single dominant gene in first and second backcrosses to BALB/c. This resistance to erythroblastosis is distinct from other genes known to affect susceptibility to Friend virus including Fv-1, Fv-2, H-2, Rfv-3, Fv-4, and Rmcf. We suggest the name Fhe for the new gene controlling susceptibility to Friend helper virus erythroblastosis. The Rockefeller University Press 1983-08-01 /pmc/articles/PMC2187339/ /pubmed/6577128 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
A new gene that controls the type of leukemia induced by Friend murine leukemia virus
title A new gene that controls the type of leukemia induced by Friend murine leukemia virus
title_full A new gene that controls the type of leukemia induced by Friend murine leukemia virus
title_fullStr A new gene that controls the type of leukemia induced by Friend murine leukemia virus
title_full_unstemmed A new gene that controls the type of leukemia induced by Friend murine leukemia virus
title_short A new gene that controls the type of leukemia induced by Friend murine leukemia virus
title_sort new gene that controls the type of leukemia induced by friend murine leukemia virus
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187339/
https://www.ncbi.nlm.nih.gov/pubmed/6577128

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