Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells

This report demonstrates directly, using two-dimensional gel electrophoresis and alloantisera, the following: (a) The DR4 light chains show a structural polymorphism among the Dw4, DKT2, and DYT cells. (b) Most of the class II light chains consist of the DR light chain. (c) The MT3 molecule is disti...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1984
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187405/
https://www.ncbi.nlm.nih.gov/pubmed/6206187
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collection PubMed
description This report demonstrates directly, using two-dimensional gel electrophoresis and alloantisera, the following: (a) The DR4 light chains show a structural polymorphism among the Dw4, DKT2, and DYT cells. (b) Most of the class II light chains consist of the DR light chain. (c) The MT3 molecule is distinct from the DR4 molecule in the Dw4, DKT2, and DYT cells. (d) The MT3 molecule does not show any structural heterogeneity among the Dw4, DKT2, and DYT cells. These results suggest that the dissection of the D specificity among Dw4, DKT2, and DYT is mainly caused by the differences of the DR4 molecules.
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spelling pubmed-21874052008-04-17 Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells J Exp Med Articles This report demonstrates directly, using two-dimensional gel electrophoresis and alloantisera, the following: (a) The DR4 light chains show a structural polymorphism among the Dw4, DKT2, and DYT cells. (b) Most of the class II light chains consist of the DR light chain. (c) The MT3 molecule is distinct from the DR4 molecule in the Dw4, DKT2, and DYT cells. (d) The MT3 molecule does not show any structural heterogeneity among the Dw4, DKT2, and DYT cells. These results suggest that the dissection of the D specificity among Dw4, DKT2, and DYT is mainly caused by the differences of the DR4 molecules. The Rockefeller University Press 1984-09-01 /pmc/articles/PMC2187405/ /pubmed/6206187 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells
title Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells
title_full Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells
title_fullStr Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells
title_full_unstemmed Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells
title_short Two-dimensional gel electrophoretic analysis of the MT3 and DR4 molecules from the different D-typed cells
title_sort two-dimensional gel electrophoretic analysis of the mt3 and dr4 molecules from the different d-typed cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187405/
https://www.ncbi.nlm.nih.gov/pubmed/6206187

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