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Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A- bearing antigen-presenting cell function
In an effort to elucidate the role of intrathymic Ia-bearing antigen- presenting cells (APC) on the development of the class II-restricted T cell repertoire, we examined the effect of neonatal anti-I-A treatment on both intrathymic and splenic APC function; on the generation of Lyt- 2-,L3T4+, Lyt-2+...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1985
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187596/ https://www.ncbi.nlm.nih.gov/pubmed/3921649 |