Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice

Administration of the monoclonal antibody M7/20, which binds to the murine interleukin-2 (IL) receptor, significantly prolongs cardiac allograft survival in two H-2-incompatible strain combinations of inbred mice. The results support the important role of the IL-2 receptor in the mechanism of graft...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1985
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187689/
https://www.ncbi.nlm.nih.gov/pubmed/3925068
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collection PubMed
description Administration of the monoclonal antibody M7/20, which binds to the murine interleukin-2 (IL) receptor, significantly prolongs cardiac allograft survival in two H-2-incompatible strain combinations of inbred mice. The results support the important role of the IL-2 receptor in the mechanism of graft rejection, and suggest its suitability as a target for immunosuppressive therapy.
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spelling pubmed-21876892008-04-17 Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice J Exp Med Articles Administration of the monoclonal antibody M7/20, which binds to the murine interleukin-2 (IL) receptor, significantly prolongs cardiac allograft survival in two H-2-incompatible strain combinations of inbred mice. The results support the important role of the IL-2 receptor in the mechanism of graft rejection, and suggest its suitability as a target for immunosuppressive therapy. The Rockefeller University Press 1985-07-01 /pmc/articles/PMC2187689/ /pubmed/3925068 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
title Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
title_full Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
title_fullStr Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
title_full_unstemmed Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
title_short Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
title_sort administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187689/
https://www.ncbi.nlm.nih.gov/pubmed/3925068

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