Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells

Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation,...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1985
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187706/
https://www.ncbi.nlm.nih.gov/pubmed/2989411
_version_ 1782146237180411904
collection PubMed
description Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation, and (c) expressed low affinity but not high affinity receptors for IL-2.
format Text
id pubmed-2187706
institution National Center for Biotechnology Information
language English
publishDate 1985
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21877062008-04-17 Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells J Exp Med Articles Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation, and (c) expressed low affinity but not high affinity receptors for IL-2. The Rockefeller University Press 1985-07-01 /pmc/articles/PMC2187706/ /pubmed/2989411 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
title Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
title_full Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
title_fullStr Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
title_full_unstemmed Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
title_short Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells
title_sort stable expression of cdna encoding the human interleukin 2 receptor in eukaryotic cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187706/
https://www.ncbi.nlm.nih.gov/pubmed/2989411

Ejemplares similares