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CD8 is required during positive selection of CD4-/CD8+ T cells
Interactions between self-MHC molecules and T cells are necessary for the proper development of mature T cells, in part due to an absolute requirement for self-MHC-TCR interactions. Recently, we showed that CD4- mediated interactions also participate in shaping the T cell repertoire during thymic ma...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1990
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187717/ https://www.ncbi.nlm.nih.gov/pubmed/1968084 |