Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse

We have determined the DNA sequence of a gene encoding a thymus leukemia (TL) antigen in the BALB/c mouse, and have more definitively mapped the cloned BALB/c Tla-region class I gene clusters. Analysis of the sequence shows that the Tla gene is less closely related to the H-2 genes than H-2 genes ar...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1985
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187753/
https://www.ncbi.nlm.nih.gov/pubmed/3894562
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collection PubMed
description We have determined the DNA sequence of a gene encoding a thymus leukemia (TL) antigen in the BALB/c mouse, and have more definitively mapped the cloned BALB/c Tla-region class I gene clusters. Analysis of the sequence shows that the Tla gene is less closely related to the H-2 genes than H-2 genes are to one another or to a Qa-2,3-region genes. The Tla gene, 17.3A, contains an apparent gene conversion. Comparison of the BALB/c Tla genes with those from C57BL shows that BALB/c has more Tla-region class I genes, and that one of the genes absent in C57BL is gene 17.3A.
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spelling pubmed-21877532008-04-17 Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse J Exp Med Articles We have determined the DNA sequence of a gene encoding a thymus leukemia (TL) antigen in the BALB/c mouse, and have more definitively mapped the cloned BALB/c Tla-region class I gene clusters. Analysis of the sequence shows that the Tla gene is less closely related to the H-2 genes than H-2 genes are to one another or to a Qa-2,3-region genes. The Tla gene, 17.3A, contains an apparent gene conversion. Comparison of the BALB/c Tla genes with those from C57BL shows that BALB/c has more Tla-region class I genes, and that one of the genes absent in C57BL is gene 17.3A. The Rockefeller University Press 1985-08-01 /pmc/articles/PMC2187753/ /pubmed/3894562 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse
title Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse
title_full Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse
title_fullStr Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse
title_full_unstemmed Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse
title_short Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse
title_sort structure of a gene encoding a murine thymus leukemia antigen, and organization of tla genes in the balb/c mouse
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187753/
https://www.ncbi.nlm.nih.gov/pubmed/3894562

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