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Lipopolysaccharide-stimulated human monocytes secrete, apart from neutrophil-activating peptide 1/interleukin 8, a second neutrophil- activating protein. NH2-terminal amino acid sequence identity with melanoma growth stimulatory activity
Purification of monocyte-derived NAP-1/IL-8 by preparative reversed- phase (RP)-HPLC led to the detection of a second peak with polymorphonuclear leukocyte (PMNL)-activating (degranulation, chemotaxis) properties. The monokine responsible for this biological activity, which we tentatively termed NAP...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187842/ https://www.ncbi.nlm.nih.gov/pubmed/2182761 |