Helper T cells reacting to idiotype on IgG but not IgM

Immunization with an IgG1 but not an IgM monoclonal anti-NP (4-hydroxy- 3-nitrophenyl acetyl) antibody induced idiotype-recognizing T helper cells, although these two antibodies carry the same variable regions. The T cells appear to react to an idiotype on the IgG1 but not the IgM antibody. They sel...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1985
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187853/
https://www.ncbi.nlm.nih.gov/pubmed/2931497
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collection PubMed
description Immunization with an IgG1 but not an IgM monoclonal anti-NP (4-hydroxy- 3-nitrophenyl acetyl) antibody induced idiotype-recognizing T helper cells, although these two antibodies carry the same variable regions. The T cells appear to react to an idiotype on the IgG1 but not the IgM antibody. They selectively enhance the expression of that idiotype in the IgG1 fraction of an in vitro anti-NP response.
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spelling pubmed-21878532008-04-17 Helper T cells reacting to idiotype on IgG but not IgM J Exp Med Articles Immunization with an IgG1 but not an IgM monoclonal anti-NP (4-hydroxy- 3-nitrophenyl acetyl) antibody induced idiotype-recognizing T helper cells, although these two antibodies carry the same variable regions. The T cells appear to react to an idiotype on the IgG1 but not the IgM antibody. They selectively enhance the expression of that idiotype in the IgG1 fraction of an in vitro anti-NP response. The Rockefeller University Press 1985-10-01 /pmc/articles/PMC2187853/ /pubmed/2931497 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Helper T cells reacting to idiotype on IgG but not IgM
title Helper T cells reacting to idiotype on IgG but not IgM
title_full Helper T cells reacting to idiotype on IgG but not IgM
title_fullStr Helper T cells reacting to idiotype on IgG but not IgM
title_full_unstemmed Helper T cells reacting to idiotype on IgG but not IgM
title_short Helper T cells reacting to idiotype on IgG but not IgM
title_sort helper t cells reacting to idiotype on igg but not igm
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187853/
https://www.ncbi.nlm.nih.gov/pubmed/2931497

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