bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia

Southern blot analysis detected a bcr gene rearrangement within leukemic cells of a Philadelphia chromosome-negative chronic myelocytic leukemia (CML) patient that led to transcription of a novel 7.3 kb bcr RNA species. Participation of the c-abl oncogene in this genomic recombination could be ruled...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1985
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187996/
https://www.ncbi.nlm.nih.gov/pubmed/2415665
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collection PubMed
description Southern blot analysis detected a bcr gene rearrangement within leukemic cells of a Philadelphia chromosome-negative chronic myelocytic leukemia (CML) patient that led to transcription of a novel 7.3 kb bcr RNA species. Participation of the c-abl oncogene in this genomic recombination could be ruled out by in situ hybridization studies and Northern blot analysis.
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spelling pubmed-21879962008-04-17 bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia J Exp Med Articles Southern blot analysis detected a bcr gene rearrangement within leukemic cells of a Philadelphia chromosome-negative chronic myelocytic leukemia (CML) patient that led to transcription of a novel 7.3 kb bcr RNA species. Participation of the c-abl oncogene in this genomic recombination could be ruled out by in situ hybridization studies and Northern blot analysis. The Rockefeller University Press 1985-12-01 /pmc/articles/PMC2187996/ /pubmed/2415665 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
title bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
title_full bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
title_fullStr bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
title_full_unstemmed bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
title_short bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
title_sort bcr rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187996/
https://www.ncbi.nlm.nih.gov/pubmed/2415665

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