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Detection of T cell receptor alpha chain locus rearrangements in human antigen-specific T lymphocyte clones using a DNA probe specific for chromosome region 14q11
Human cloned antigen-specific T lymphocytes were used to characterize DNA rearrangements using a cDNA probe from the T cell receptor (TCR)- alpha chain gene. Rearranged patterns were detected in some T cell clones, confirming that normal mature T cells are rearranged in TCR- alpha locus. Similarly,...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1986
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188096/ https://www.ncbi.nlm.nih.gov/pubmed/3486246 |