Gamma gene rearrangement and expression in autoreactive helper T cells

gamma gene rearrangements similar to those described for cytotoxic T cell lines are found in L3T4+, autoreactive, or KLH-specific cloned helper T cell lines. High levels of gamma RNA transcripts were, in addition, detected in four out of five L3T4+, class II MHC-specific, autoreactive T cell clones,...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1986
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188103/
https://www.ncbi.nlm.nih.gov/pubmed/2939171
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collection PubMed
description gamma gene rearrangements similar to those described for cytotoxic T cell lines are found in L3T4+, autoreactive, or KLH-specific cloned helper T cell lines. High levels of gamma RNA transcripts were, in addition, detected in four out of five L3T4+, class II MHC-specific, autoreactive T cell clones, and in at least one of three KLH-specific, class II MHC-restricted clones. This contrasts with previously reported (9) expression of gamma RNA in only 1 of 11 antigen-specific helper T cell lines.
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spelling pubmed-21881032008-04-17 Gamma gene rearrangement and expression in autoreactive helper T cells J Exp Med Articles gamma gene rearrangements similar to those described for cytotoxic T cell lines are found in L3T4+, autoreactive, or KLH-specific cloned helper T cell lines. High levels of gamma RNA transcripts were, in addition, detected in four out of five L3T4+, class II MHC-specific, autoreactive T cell clones, and in at least one of three KLH-specific, class II MHC-restricted clones. This contrasts with previously reported (9) expression of gamma RNA in only 1 of 11 antigen-specific helper T cell lines. The Rockefeller University Press 1986-05-01 /pmc/articles/PMC2188103/ /pubmed/2939171 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Gamma gene rearrangement and expression in autoreactive helper T cells
title Gamma gene rearrangement and expression in autoreactive helper T cells
title_full Gamma gene rearrangement and expression in autoreactive helper T cells
title_fullStr Gamma gene rearrangement and expression in autoreactive helper T cells
title_full_unstemmed Gamma gene rearrangement and expression in autoreactive helper T cells
title_short Gamma gene rearrangement and expression in autoreactive helper T cells
title_sort gamma gene rearrangement and expression in autoreactive helper t cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188103/
https://www.ncbi.nlm.nih.gov/pubmed/2939171

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