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Retinoic acid-induced gene expression in normal and leukemic myeloid cells

Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutamina...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1986
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188109/
https://www.ncbi.nlm.nih.gov/pubmed/2871126
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description Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutaminase mRNA levels in human promyelocytic leukemia (HL- 60) cells. These studies show that retinoic acid can induce acute alterations in specific gene expression in both normal and leukemic myeloid cells.
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spelling pubmed-21881092008-04-17 Retinoic acid-induced gene expression in normal and leukemic myeloid cells J Exp Med Articles Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutaminase mRNA levels in human promyelocytic leukemia (HL- 60) cells. These studies show that retinoic acid can induce acute alterations in specific gene expression in both normal and leukemic myeloid cells. The Rockefeller University Press 1986-05-01 /pmc/articles/PMC2188109/ /pubmed/2871126 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Retinoic acid-induced gene expression in normal and leukemic myeloid cells
title Retinoic acid-induced gene expression in normal and leukemic myeloid cells
title_full Retinoic acid-induced gene expression in normal and leukemic myeloid cells
title_fullStr Retinoic acid-induced gene expression in normal and leukemic myeloid cells
title_full_unstemmed Retinoic acid-induced gene expression in normal and leukemic myeloid cells
title_short Retinoic acid-induced gene expression in normal and leukemic myeloid cells
title_sort retinoic acid-induced gene expression in normal and leukemic myeloid cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188109/
https://www.ncbi.nlm.nih.gov/pubmed/2871126