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Retinoic acid-induced gene expression in normal and leukemic myeloid cells
Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutamina...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1986
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188109/ https://www.ncbi.nlm.nih.gov/pubmed/2871126 |
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collection | PubMed |
description | Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutaminase mRNA levels in human promyelocytic leukemia (HL- 60) cells. These studies show that retinoic acid can induce acute alterations in specific gene expression in both normal and leukemic myeloid cells. |
format | Text |
id | pubmed-2188109 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1986 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21881092008-04-17 Retinoic acid-induced gene expression in normal and leukemic myeloid cells J Exp Med Articles Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutaminase mRNA levels in human promyelocytic leukemia (HL- 60) cells. These studies show that retinoic acid can induce acute alterations in specific gene expression in both normal and leukemic myeloid cells. The Rockefeller University Press 1986-05-01 /pmc/articles/PMC2188109/ /pubmed/2871126 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Retinoic acid-induced gene expression in normal and leukemic myeloid cells |
title | Retinoic acid-induced gene expression in normal and leukemic myeloid cells |
title_full | Retinoic acid-induced gene expression in normal and leukemic myeloid cells |
title_fullStr | Retinoic acid-induced gene expression in normal and leukemic myeloid cells |
title_full_unstemmed | Retinoic acid-induced gene expression in normal and leukemic myeloid cells |
title_short | Retinoic acid-induced gene expression in normal and leukemic myeloid cells |
title_sort | retinoic acid-induced gene expression in normal and leukemic myeloid cells |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188109/ https://www.ncbi.nlm.nih.gov/pubmed/2871126 |