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The fifth component of complement (C5) in the mouse. Analysis of the molecular basis for deficiency

C5-deficient mice differed from C5-sufficient mice both quantitatively and qualitatively in C5 protein, C5 mRNA, and the C5 gene. C5-deficient protein was present as decreased amounts of an unprocessed, single- chain precursor. C5-deficient mRNA was decreased in amount and present in two forms, the...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1987
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188303/
https://www.ncbi.nlm.nih.gov/pubmed/3572304