Cargando…
Idiotypic self binding of a dominant germline idiotype (T15). Autobody activity is affected by antibody valency
We have previously described (1-3) an IgM antibody that binds to PC, expresses the T15 idiotype, and binds also to itself or T15 if insolubilized. Because of the simultaneous presence of complementary idiotopes and paratopes this type of antibody has been termed autobody. The self binding involves t...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1987
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188311/ https://www.ncbi.nlm.nih.gov/pubmed/3106554 |
Ejemplares similares
-
Idiotypic regulation of the immune system. Common idiotypic specificities between idiotypes and antibodies raised against anti- idiotypic antibodies in rabbits
Publicado: (1979) -
Antigen binding and idiotype analysis of antibodies obtained after electroporation of heavy and light chain genes encoding phosphocholine- specific antibodies: a model for T15-idiotype dominance
Publicado: (1992) -
Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. II. Transient idiotypic dominance
Publicado: (1981) -
Idiotype-anti-idiotype network. II. Activation of silent clones by treatment at birth with idiotypes is associated with the expansion of idiotype-specific helper T cells
Publicado: (1982) -
Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones
Publicado: (1981)