The B cell antigen CD75 is a cell surface sialytransferase

In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human alpha 2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression o...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1990
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188328/
https://www.ncbi.nlm.nih.gov/pubmed/2373995
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collection PubMed
description In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human alpha 2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialytransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.
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spelling pubmed-21883282008-04-17 The B cell antigen CD75 is a cell surface sialytransferase J Exp Med Articles In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human alpha 2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialytransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events. The Rockefeller University Press 1990-08-01 /pmc/articles/PMC2188328/ /pubmed/2373995 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
The B cell antigen CD75 is a cell surface sialytransferase
title The B cell antigen CD75 is a cell surface sialytransferase
title_full The B cell antigen CD75 is a cell surface sialytransferase
title_fullStr The B cell antigen CD75 is a cell surface sialytransferase
title_full_unstemmed The B cell antigen CD75 is a cell surface sialytransferase
title_short The B cell antigen CD75 is a cell surface sialytransferase
title_sort b cell antigen cd75 is a cell surface sialytransferase
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188328/
https://www.ncbi.nlm.nih.gov/pubmed/2373995

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