Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats

Preoperative, donor-specific blood transfusion leads to indefinite survival of rat renal allografts in the strain combinations used. 51Cr- release assays have shown that the level of specific cytotoxic effector activity in the grafts of transfused (nonrejected kidney) animals is very high and may eq...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1987
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188510/
https://www.ncbi.nlm.nih.gov/pubmed/3546578
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collection PubMed
description Preoperative, donor-specific blood transfusion leads to indefinite survival of rat renal allografts in the strain combinations used. 51Cr- release assays have shown that the level of specific cytotoxic effector activity in the grafts of transfused (nonrejected kidney) animals is very high and may equal or exceed that seen in the grafts of untreated (rejected kidney) recipients. Such cytotoxicity demonstrates specificity for the alloantigens of the kidney, is T cell-mediated, and may persist within the transplant.
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spelling pubmed-21885102008-04-17 Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats J Exp Med Articles Preoperative, donor-specific blood transfusion leads to indefinite survival of rat renal allografts in the strain combinations used. 51Cr- release assays have shown that the level of specific cytotoxic effector activity in the grafts of transfused (nonrejected kidney) animals is very high and may equal or exceed that seen in the grafts of untreated (rejected kidney) recipients. Such cytotoxicity demonstrates specificity for the alloantigens of the kidney, is T cell-mediated, and may persist within the transplant. The Rockefeller University Press 1987-02-01 /pmc/articles/PMC2188510/ /pubmed/3546578 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
title Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
title_full Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
title_fullStr Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
title_full_unstemmed Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
title_short Specific cytotoxic T cells are found in the nonrejected kidneys of blood-transfused rats
title_sort specific cytotoxic t cells are found in the nonrejected kidneys of blood-transfused rats
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188510/
https://www.ncbi.nlm.nih.gov/pubmed/3546578

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