Cargando…
Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes
Human cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleoproteins of influenza virus in association with MHC...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1987
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188513/ https://www.ncbi.nlm.nih.gov/pubmed/3029268 |
_version_ | 1782146426044678144 |
---|---|
collection | PubMed |
description | Human cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleoproteins of influenza virus in association with MHC class I antigens. These internal viral proteins were seen by CTL in conjunction with one or more of the available dependent HLA gene products. There was no detectable recognition of influenza virus surface glycoproteins in target cells. |
format | Text |
id | pubmed-2188513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1987 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21885132008-04-17 Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes J Exp Med Articles Human cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleoproteins of influenza virus in association with MHC class I antigens. These internal viral proteins were seen by CTL in conjunction with one or more of the available dependent HLA gene products. There was no detectable recognition of influenza virus surface glycoproteins in target cells. The Rockefeller University Press 1987-02-01 /pmc/articles/PMC2188513/ /pubmed/3029268 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes |
title | Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes |
title_full | Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes |
title_fullStr | Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes |
title_full_unstemmed | Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes |
title_short | Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes |
title_sort | identification of viral molecules recognized by influenza-specific human cytotoxic t lymphocytes |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188513/ https://www.ncbi.nlm.nih.gov/pubmed/3029268 |