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Oral Salmonella: malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells
Oral immunization with an attenuated Salmonella typhimurium recombinant containing the full-length Plasmodium berghei circumsporozoite (CS) gene induces protective immunity against P. berghei sporozoite challenge in the absence of antibody. We found that this immunity was mediated through the induct...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1990
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188594/ https://www.ncbi.nlm.nih.gov/pubmed/1698908 |