Cargando…

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses

We describe here a monoclonal antibody (H398) that immunoprecipitates a human 60-kD tumor necrosis factor (TNF) membrane receptor (p60) and competes with TNF binding to p60 but not to p85 TNF receptors. Despite partial inhibition of TNF binding capacity of cells coexpressing both TNF receptor molecu...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1990
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188608/ https://www.ncbi.nlm.nih.gov/pubmed/2170559

Ejemplares similares

A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes
Publicado: (1995)

Zinc finger domain of Ro60kD autoantigen is essential for binding of Ro52kD and autoantibodies
por: Routsias, JG, et al.
Publicado: (2003)

Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity
Publicado: (1994)

A major 62-kD intranuclear matrix polypeptide is a component of metaphase chromosomes
Publicado: (1988)

Secretion of heat shock ‐60, ‐70 kD protein, IL‐1β and TNFα levels in serum of a term normal pregnancy and patients with pre‐eclampsia development
por: Álvarez‐Cabrera, María C., et al.
Publicado: (2018)

Tumor necrosis factor-α, TNF receptor, and soluble TNF receptor responses to aerobic exercise in the heat
por: Arroyo, Eliott, et al.
Publicado: (2020)

Immune Sensitization to the 60 kD Heat Shock Protein and Pregnancy Outcome
por: Neuer, A., et al.
Publicado: (1997)

Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils
Publicado: (1991)

Detection of the human 70-kD and 60-kD heat shock proteins in the vagina: relation to microbial flora, vaginal pH, and method of contraception.
por: Giraldo, P, et al.
Publicado: (1999)

Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor
Publicado: (1996)

Immune Recognition of the 60kD Heat Shock Protein: Implications for Subsequent Fertility
por: Witkin, Steven S., et al.
Publicado: (1996)

Cytoplasmic components of acetylcholine receptor clusters of cultured rat myotubes: the 58-kD protein
Publicado: (1991)

Common Gene Variants in the Tumor Necrosis Factor (TNF) and TNF Receptor Superfamilies and NF-kB Transcription Factors and Non-Hodgkin Lymphoma Risk
por: Wang, Sophia S., et al.
Publicado: (2009)

Antiviral Activity of Tumor Necrosis Factor (TNF) Is Mediated via p55 and p75 TNF Receptors
por: Ruby, Janet, et al.
Publicado: (1997)

60 kD Ro and nRNP A Frequently Initiate Human Lupus Autoimmunity
por: Heinlen, Latisha D., et al.
Publicado: (2010)

Functional characterization of the 180-kD ribosome receptor in vivo
Publicado: (1995)

Major loss of the 28-kD protein of gap junction in proliferating hepatocytes
Publicado: (1987)

Induced Expression of Trimerized Intracellular Domains of the Human Tumor Necrosis Factor (TNF) p55 Receptor Elicits TNF Effects
por: Vandevoorde, Veronique, et al.
Publicado: (1997)

Tumor Necrosis Factor (TNF) Receptor Expression Determines Keratinocyte Fate upon Stimulation with TNF-Like Weak Inducer of Apoptosis
por: Wang, Xuening, et al.
Publicado: (2019)

Identification of Grb2 As a Novel Binding Partner of Tumor Necrosis Factor (TNF) Receptor I
por: Hildt, Eberhard, et al.
Publicado: (1999)

Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
por: Yang, Sujuan, et al.
Publicado: (2018)

The evolution of TNF signaling in platyhelminths suggests the cooptation of TNF receptor in the host-parasite interplay
por: Bertevello, Claudio R., et al.
Publicado: (2020)

Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils
Publicado: (1986)

Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55
Publicado: (1993)

The transmembrane signaling pathway involved in directed movements of Chlamydomonas flagellar membrane glycoproteins involves the dephosphorylation of a 60-kD phosphoprotein that binds to the major flagellar membrane glycoprotein
Publicado: (1994)

Comparative characterization of the 21-kD and 26-kD gap junction proteins in murine liver and cultured hepatocytes
Publicado: (1989)

Structural insights of homotypic interaction domains in the ligand-receptor signal transduction of tumor necrosis factor (TNF)
por: Park, Young-Hoon, et al.
Publicado: (2016)

A new 440-kD isoform is the major ankyrin in neonatal rat brain
Publicado: (1991)

A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
Publicado: (1991)

A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon
Publicado: (1994)

TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors
por: Sheng, Yuqiao, et al.
Publicado: (2018)

A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF-R) in Organ Inflammation Independent of TNF, Lymphotoxin α, or the p55TNF-R
por: Douni, Eleni, et al.
Publicado: (1998)

Cause-effect relations between 55 kD soluble TNF receptor concentrations and specific and unspecific symptoms in a patient with mild SLE disease activity: an exploratory time series analysis study
por: Schubert, Christian, et al.
Publicado: (2015)

The benefits of clustering in TNF receptor superfamily signaling
por: Vanamee, Éva S., et al.
Publicado: (2023)

Identification of a 200-kD, brefeldin-sensitive protein on Golgi membranes
Publicado: (1992)

The antitumor function of tumor necrosis factor (TNF) II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma
Publicado: (1988)

Prothrombotic effects of tumor necrosis factor alpha in vivo are amplified by the absence of TNF-alpha receptor subtype 1 and require TNF-alpha receptor subtype 2
por: Pircher, Joachim, et al.
Publicado: (2012)

Tumor Necrosis Factor-α and Lymphotoxin-α Mediate Myocardial Ischemic Injury via TNF Receptor 1, but Are Cardioprotective When Activating TNF Receptor 2
por: Zhang, Yanqing, et al.
Publicado: (2013)

Tumor Necrosis Factor (TNF) Receptor Shedding Controls Thresholds of Innate Immune Activation That Balance Opposing TNF Functions in Infectious and Inflammatory Diseases
por: Xanthoulea, Sofia, et al.
Publicado: (2004)

The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics
por: Jang, Dan-in, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i0mq3cs5kbpmv3d41ngvnsuj6m