Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages

We have studied the distribution of talin in J774 cells and mouse peritoneal macrophages undergoing Fc receptor-mediated phagocytosis. At early stages of phagocytosis, talin accumulates in the cells' cortical cytoplasm adjacent to the forming phagosome and extends into pseudopods that are encir...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1990
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188739/
https://www.ncbi.nlm.nih.gov/pubmed/2124254
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collection PubMed
description We have studied the distribution of talin in J774 cells and mouse peritoneal macrophages undergoing Fc receptor-mediated phagocytosis. At early stages of phagocytosis, talin accumulates in the cells' cortical cytoplasm adjacent to the forming phagosome and extends into pseudopods that are encircling the particle. Talin colocalizes with F-actin at these sites. After particle ingestion is completed, F-actin and talin are no longer concentrated adjacent to phagosomes. Thus, talin and F- actin undergo dynamic and coordinate changes in their cytoplasmic location during Fc receptor-mediated phagocytosis.
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spelling pubmed-21887392008-04-17 Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages J Exp Med Articles We have studied the distribution of talin in J774 cells and mouse peritoneal macrophages undergoing Fc receptor-mediated phagocytosis. At early stages of phagocytosis, talin accumulates in the cells' cortical cytoplasm adjacent to the forming phagosome and extends into pseudopods that are encircling the particle. Talin colocalizes with F-actin at these sites. After particle ingestion is completed, F-actin and talin are no longer concentrated adjacent to phagosomes. Thus, talin and F- actin undergo dynamic and coordinate changes in their cytoplasmic location during Fc receptor-mediated phagocytosis. The Rockefeller University Press 1990-12-01 /pmc/articles/PMC2188739/ /pubmed/2124254 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages
title Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages
title_full Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages
title_fullStr Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages
title_full_unstemmed Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages
title_short Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages
title_sort colocalization of f-actin and talin during fc receptor-mediated phagocytosis in mouse macrophages
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188739/
https://www.ncbi.nlm.nih.gov/pubmed/2124254

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