Cargando…
Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias
Although acute promyelocytic leukemias (APLs) are consistently associated with a reciprocal chromosome 15;17 translocation, the gene(s) directly affected by the breakpoints have never been isolated. The chromosome 17 breakpoint maps to near the retinoic acid receptor alpha (RAR alpha) locus. Investi...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1990
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188762/ https://www.ncbi.nlm.nih.gov/pubmed/2175343 |
Ejemplares similares
-
Significance of ETV6 rearrangement in acute promyelocytic leukemia with t(15;17)/promyelocytic leukemia/retinoic acid receptor alpha
por: GAO, NA, et al.
Publicado: (2016) -
Transcriptional features of acute leukemia with promyelocytic differentiation lacking retinoic acid receptor rearrangements
por: Su, Zhan, et al.
Publicado: (2023) -
Acute Myeloid Leukemia Acquiring Promyelocytic Leukemia-Retinoic Acid Receptor Alpha at Relapse
por: Gupta, Varsha, et al.
Publicado: (2019) -
The Pleiotropic Role of Retinoic Acid/Retinoic Acid Receptors Signaling: From Vitamin A Metabolism to Gene Rearrangements in Acute Promyelocytic Leukemia
por: Conserva, Maria Rosa, et al.
Publicado: (2019) -
2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia
por: Lu, Ying, et al.
Publicado: (2019)