Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element

The adoptive transfer of clinical and histopathologic signs of experimental allergic encephalomyelitis (EAE) requires MHC compatibility between cell donor and cell recipient. The results of adoptive transfer studies using F1 to parent bone marrow chimeras as recipients of parental-derived BP-sensiti...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1987
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188803/
https://www.ncbi.nlm.nih.gov/pubmed/3316476
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description The adoptive transfer of clinical and histopathologic signs of experimental allergic encephalomyelitis (EAE) requires MHC compatibility between cell donor and cell recipient. The results of adoptive transfer studies using F1 to parent bone marrow chimeras as recipients of parental-derived BP-sensitive spleen cells indicate that this restriction is not expressed at the level of the endothelial cell but is confined to the cells of bone marrow derivation. Furthermore, these results indicate that the development of EAE is not dependent on the activity of MHC-restricted cytotoxic cells.
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spelling pubmed-21888032008-04-17 Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element J Exp Med Articles The adoptive transfer of clinical and histopathologic signs of experimental allergic encephalomyelitis (EAE) requires MHC compatibility between cell donor and cell recipient. The results of adoptive transfer studies using F1 to parent bone marrow chimeras as recipients of parental-derived BP-sensitive spleen cells indicate that this restriction is not expressed at the level of the endothelial cell but is confined to the cells of bone marrow derivation. Furthermore, these results indicate that the development of EAE is not dependent on the activity of MHC-restricted cytotoxic cells. The Rockefeller University Press 1987-12-01 /pmc/articles/PMC2188803/ /pubmed/3316476 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element
title Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element
title_full Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element
title_fullStr Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element
title_full_unstemmed Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element
title_short Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element
title_sort transfer of experimental allergic encephalomyelitis to bone marrow chimeras. endothelial cells are not a restricting element
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188803/
https://www.ncbi.nlm.nih.gov/pubmed/3316476

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