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Peptides bound to proteosomes via hydrophobic feet become highly immunogenic without adjuvants
Addition of either a lauroyl or a pentapeptide (FLLAV) hydrophobic foot to the NH2 terminus of a small, synthetic peptide allowed the peptide to hydrophobically complex to meningococcal outer membrane protein proteosomes by simple dialysis. Both conventional and LPS- hyporesponsive mice immunized wi...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188847/ https://www.ncbi.nlm.nih.gov/pubmed/3346624 |