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Immunogenicity of liposome-bound hyaluronate in mice. At least two different antigenic sites on hyaluronate are identified by mouse monoclonal antibodies
Hyaluronate (HA) was previously demonstrated to be immunogenic in rabbits. The immunogenicity of HA in mice was studied. Hyaluronidase- digested streptococcal HA (IA1) covalently linked to liposomes (IA1- liposomes) were produced for immunization. Mice immunized with IA1- liposomes developed measura...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1988
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189035/ https://www.ncbi.nlm.nih.gov/pubmed/2459294 |