Cargando…
A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1
The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this o...
| Formato: | Texto |
|---|---|
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1989
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224/ https://www.ncbi.nlm.nih.gov/pubmed/2564418 |
| _version_ | 1782146592265994240 |
|---|---|
| collection | PubMed |
| description | The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset. |
| format | Text |
| id | pubmed-2189224 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1989 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21892242008-04-17 A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 J Exp Med Articles The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset. The Rockefeller University Press 1989-04-01 /pmc/articles/PMC2189224/ /pubmed/2564418 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Articles A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 |
| title | A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 |
| title_full | A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 |
| title_fullStr | A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 |
| title_full_unstemmed | A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 |
| title_short | A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1 |
| title_sort | subset of memory cd4+ helper t lymphocytes identified by expression of pgp-1 |
| topic | Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189224/ https://www.ncbi.nlm.nih.gov/pubmed/2564418 |