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Human monocytes can produce tissue-type plasminogen activator

Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen activator (t-PA) of 70 kD. Detection of t-PA mRNA was...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189243/
https://www.ncbi.nlm.nih.gov/pubmed/2494295
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description Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen activator (t-PA) of 70 kD. Detection of t-PA mRNA was consistent with the biochemical and immunological characterization of t-PA produced by human monocytes.
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spelling pubmed-21892432008-04-17 Human monocytes can produce tissue-type plasminogen activator J Exp Med Articles Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen activator (t-PA) of 70 kD. Detection of t-PA mRNA was consistent with the biochemical and immunological characterization of t-PA produced by human monocytes. The Rockefeller University Press 1989-04-01 /pmc/articles/PMC2189243/ /pubmed/2494295 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Human monocytes can produce tissue-type plasminogen activator
title Human monocytes can produce tissue-type plasminogen activator
title_full Human monocytes can produce tissue-type plasminogen activator
title_fullStr Human monocytes can produce tissue-type plasminogen activator
title_full_unstemmed Human monocytes can produce tissue-type plasminogen activator
title_short Human monocytes can produce tissue-type plasminogen activator
title_sort human monocytes can produce tissue-type plasminogen activator
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189243/
https://www.ncbi.nlm.nih.gov/pubmed/2494295