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Human monocytes can produce tissue-type plasminogen activator
Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen activator (t-PA) of 70 kD. Detection of t-PA mRNA was...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1989
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189243/ https://www.ncbi.nlm.nih.gov/pubmed/2494295 |
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collection | PubMed |
description | Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen activator (t-PA) of 70 kD. Detection of t-PA mRNA was consistent with the biochemical and immunological characterization of t-PA produced by human monocytes. |
format | Text |
id | pubmed-2189243 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1989 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21892432008-04-17 Human monocytes can produce tissue-type plasminogen activator J Exp Med Articles Evidence has previously been presented that monocytes and macrophages produce urokinase-type plasminogen activator. We have shown for the first time that human monocytes, when stimulated appropriately in vitro, can produce tissue type-plasminogen activator (t-PA) of 70 kD. Detection of t-PA mRNA was consistent with the biochemical and immunological characterization of t-PA produced by human monocytes. The Rockefeller University Press 1989-04-01 /pmc/articles/PMC2189243/ /pubmed/2494295 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Human monocytes can produce tissue-type plasminogen activator |
title | Human monocytes can produce tissue-type plasminogen activator |
title_full | Human monocytes can produce tissue-type plasminogen activator |
title_fullStr | Human monocytes can produce tissue-type plasminogen activator |
title_full_unstemmed | Human monocytes can produce tissue-type plasminogen activator |
title_short | Human monocytes can produce tissue-type plasminogen activator |
title_sort | human monocytes can produce tissue-type plasminogen activator |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189243/ https://www.ncbi.nlm.nih.gov/pubmed/2494295 |