Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype

A set of new mouse strains were produced that carry the V beta a haplotype of the TCR-alpha/beta and any of a number of different H-2 haplotypes on backgrounds derived from related C57BL, C57L, and C57BR mice. Study of V beta 17a expression in these mice confirms the association between the presence...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1989
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189295/
https://www.ncbi.nlm.nih.gov/pubmed/2523951
_version_ 1782146608918429696
collection PubMed
description A set of new mouse strains were produced that carry the V beta a haplotype of the TCR-alpha/beta and any of a number of different H-2 haplotypes on backgrounds derived from related C57BL, C57L, and C57BR mice. Study of V beta 17a expression in these mice confirms the association between the presence of IE and the deletion of V beta 17a+ T cells. A second H-2 gene causing deletion of V beta 17a+ T cells was mapped in these mice to the K end of H-2k, and H-2 influences on the level of selection of CD4+ V beta 17a+ T cells were indicated.
format Text
id pubmed-2189295
institution National Center for Biotechnology Information
language English
publishDate 1989
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21892952008-04-17 Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype J Exp Med Articles A set of new mouse strains were produced that carry the V beta a haplotype of the TCR-alpha/beta and any of a number of different H-2 haplotypes on backgrounds derived from related C57BL, C57L, and C57BR mice. Study of V beta 17a expression in these mice confirms the association between the presence of IE and the deletion of V beta 17a+ T cells. A second H-2 gene causing deletion of V beta 17a+ T cells was mapped in these mice to the K end of H-2k, and H-2 influences on the level of selection of CD4+ V beta 17a+ T cells were indicated. The Rockefeller University Press 1989-05-01 /pmc/articles/PMC2189295/ /pubmed/2523951 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype
title Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype
title_full Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype
title_fullStr Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype
title_full_unstemmed Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype
title_short Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype
title_sort analysis of v beta 17a expression in new mouse strains bearing the v beta a haplotype
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189295/
https://www.ncbi.nlm.nih.gov/pubmed/2523951

Ejemplares similares