Cargando…

Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line

A murine B cell lymphoma (38C13) was subjected to immunoselection with mAbs directed against the idiotypic determinants of its cell surface Ig. Variants emerged with altered Ig receptors containing identical heavy chains but different light chains. The functional light chain genes in these variants...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1989
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189373/ https://www.ncbi.nlm.nih.gov/pubmed/2501443

Ejemplares similares

Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription
Publicado: (1991)

Amino acids at the site of V kappa-J kappa recombination not encoded by germline sequences
Publicado: (1987)

The kappa-deleting element. Germline and rearranged, duplicated and dispersed forms
Publicado: (1988)

Restricted kappa chain expression in early ontogeny: biased utilization of V kappa exons and preferential V kappa-J kappa recombinations
Publicado: (1993)

Preferential rearrangement of V kappa 4 gene segments in pre-B cell lines
Publicado: (1990)

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes
por: McBride, OW, et al.
Publicado: (1982)

Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles
Publicado: (1991)

Alternative V kappa gene rearrangements in a murine B cell lymphoma. An explantation for idiotypic heterogeneity
Publicado: (1988)

A conserved human germline V kappa gene directly encodes rheumatoid factor light chains
Publicado: (1986)

Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci
Publicado: (1993)

Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
por: Schmidt, Marcus, et al.
Publicado: (2012)

A murine hybridoma with large cytoplasmic inclusions of kappa light chains
Publicado: (1987)

Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines
Publicado: (1987)

BENCE JONES PROTEINS AND LIGHT CHAINS OF IMMUNOGLOBULINS : II. IMMUNOCHEMICAL DIFFERENTIATION AND CLASSIFICATION OF KAPPA-CHAINS
por: Solomon, Alan, et al.
Publicado: (1969)

Murine V kappa gene expression does not follow the VH paradigm
Publicado: (1989)

Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains
Publicado: (1984)

Cerebrospinal Fluid Immunoglobulin Kappa Light Chain in Clinically Isolated Syndrome and Multiple Sclerosis
por: Senel, Makbule, et al.
Publicado: (2014)

The Proximal J Kappa Germline-Transcript Promoter Facilitates Receptor Editing through Control of Ordered Recombination
por: Vettermann, Christian, et al.
Publicado: (2015)

Sequence similarities among kappa IIIb chains of monoclonal human IgM kappa autoantibodies
Publicado: (1984)

Kappa /
por: Akutagawa, Ryūnosuke, 1892-1927
Publicado: (1985)

Unusual patterns of immunoglobulin gene rearrangement and expression during human B cell ontogeny: human B cells can simultaneously express cell surface kappa and lambda light chains
Publicado: (1993)

Kappa light-chain amyloidosis of gastrointestinal tract
por: Hashimoto, Rintaro, et al.
Publicado: (2019)

Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages
Publicado: (1996)

Study of the $\pi^{-}$p interactions at 85 GeV/c leading to $\kappa^{+}\kappa^{+}\kappa$ $^{-}\kappa^{-}$ in the final state - search for new states
por: Booth, P S L, et al.
Publicado: (1979)

Study of the $\pi^{-}$p interactions at 85 GeV/c leading to $\kappa^{+}\kappa^{+}\kappa$ $^{-}\kappa^{-}$ in the final state - search for new states
por: Booth, P S L, et al.
Publicado: (1979)

Kappa ; Los engranajes
por: Akutagawa, Ryåunosuke, 1892-1927
Publicado: (1959)

Novel renal replacement strategies for the elimination of serum free light chains in patients with kappa light chain nephropathy
por: Kleeberg, L, et al.
Publicado: (2009)

Combined Higgs measurements STXS and kappas, including kappa interpretations
por: Mungo, Davide Pietro
Publicado: (2020)

Atypical Nodular Pulmonary Kappa Light-Chain Deposition
por: Nellipudi, Jessy, et al.
Publicado: (2021)

Lung and breast cancer research: immunoglobulin Kappa C hits the headlines
por: Marchan, Rosemarie
Publicado: (2012)

Prognostic Impact of Immunoglobulin Kappa C (IGKC) in Early Breast Cancer
por: Schmidt, Marcus, et al.
Publicado: (2021)

Evidence for an Intrathecal Immunoglobulin Synthesis by Kappa Free Light Chains in Neurological Patients with an Isolated Band in Isoelectric Focusing
por: Weiss, Bastian, et al.
Publicado: (2022)

Higgs $\kappa_{c}$ vs $\kappa_{b}$ constraint summary plot
por: The ATLAS collaboration
Publicado: (2022)

Construction and Characterization of Single-Chain Variable Fragment Antibody Library Derived from Germline Rearranged Immunoglobulin Variable Genes
por: Cheng, Man, et al.
Publicado: (2011)

Asterias rubens: Evidence of NF-kappa B genes
por: Leclerc, Michel, et al.
Publicado: (2016)

Pre-B and B cells in rabbits. Ontogeny and allelic exclusion of kappa light chain genes
Publicado: (1978)

LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells
por: Liu, HaiDan, et al.
Publicado: (2009)

Intrathecal kappa free light chains as markers for multiple sclerosis
por: Vecchio, D., et al.
Publicado: (2020)

The Use of Kappa Free Light Chains to Diagnose Multiple Sclerosis
por: Arneth, Borros, et al.
Publicado: (2022)

Kappa and Beyond: Is There Agreement?
por: Dettori, Joseph R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ts3585jnk32et6bkn3r348j0p4