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An enhancer factor defect in a mutant Burkitt lymphoma cell line
RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for th...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1988
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189699/ https://www.ncbi.nlm.nih.gov/pubmed/3133441 |
| _version_ | 1782146691496935424 |
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| collection | PubMed |
| description | RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for the activity of an MHC class II gene enhancer. |
| format | Text |
| id | pubmed-2189699 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1988 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21896992008-04-17 An enhancer factor defect in a mutant Burkitt lymphoma cell line J Exp Med Articles RJ 2.2.5 is an immunoselected mutant of the Burkitt lymphoma line Raji. It fails to display MHC class II antigens at the cell surface due to a transcriptional defect. We have identified the function of a regulatory factor that is defective in RJ 2.2.5 cells; this factor is absolutely required for the activity of an MHC class II gene enhancer. The Rockefeller University Press 1988-06-01 /pmc/articles/PMC2189699/ /pubmed/3133441 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Articles An enhancer factor defect in a mutant Burkitt lymphoma cell line |
| title | An enhancer factor defect in a mutant Burkitt lymphoma cell line |
| title_full | An enhancer factor defect in a mutant Burkitt lymphoma cell line |
| title_fullStr | An enhancer factor defect in a mutant Burkitt lymphoma cell line |
| title_full_unstemmed | An enhancer factor defect in a mutant Burkitt lymphoma cell line |
| title_short | An enhancer factor defect in a mutant Burkitt lymphoma cell line |
| title_sort | enhancer factor defect in a mutant burkitt lymphoma cell line |
| topic | Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189699/ https://www.ncbi.nlm.nih.gov/pubmed/3133441 |