Endoplasmic Reticulum Degradation Requires Lumen to Cytosol Signaling: Transmembrane Control of Hrd1p by Hrd3p

Endoplasmic reticulum (ER)-associated degradation (ERAD) is required for ubiquitin-mediated destruction of numerous proteins. ERAD occurs by processes on both sides of the ER membrane, including lumenal substrate scanning and cytosolic destruction by the proteasome. The ER resident membrane proteins...

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Detalles Bibliográficos
Autores principales: Gardner, Richard G., Swarbrick, Gwendolyn M., Bays, Nathan W., Cronin, Stephen R., Wilhovsky, Sharon, Seelig, Linda, Kim, Christine, Hampton, Randolph Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189800/
https://www.ncbi.nlm.nih.gov/pubmed/11018054

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