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Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury

During blood coagulation ultrastructural lesions were produced on the platelet membrane. They were dependent on the presence of both thrombin and complement (C) and were morphologically identical to the C- dependent ultrastructural lesions (type II) seen in red cells subsequent to activation of C by...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189843/
https://www.ncbi.nlm.nih.gov/pubmed/805209
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collection PubMed
description During blood coagulation ultrastructural lesions were produced on the platelet membrane. They were dependent on the presence of both thrombin and complement (C) and were morphologically identical to the C- dependent ultrastructural lesions (type II) seen in red cells subsequent to activation of C by the alternate mechanismmthough similar in shape they differed in size from ultrastructural lesions (type I) PRODUCED BY ACTIVATION OF C via the classic mechanismmlesions of type I were seen on the platelet surface subsequent to antibody-dependent activation of the C system.
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spelling pubmed-21898432008-04-17 Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury J Exp Med Articles During blood coagulation ultrastructural lesions were produced on the platelet membrane. They were dependent on the presence of both thrombin and complement (C) and were morphologically identical to the C- dependent ultrastructural lesions (type II) seen in red cells subsequent to activation of C by the alternate mechanismmthough similar in shape they differed in size from ultrastructural lesions (type I) PRODUCED BY ACTIVATION OF C via the classic mechanismmlesions of type I were seen on the platelet surface subsequent to antibody-dependent activation of the C system. The Rockefeller University Press 1975-06-01 /pmc/articles/PMC2189843/ /pubmed/805209 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
title Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
title_full Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
title_fullStr Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
title_full_unstemmed Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
title_short Ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
title_sort ultrastructural lesions on the surface of platelets associated with either blood coagulation or with antibody-mediated immune injury
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189843/
https://www.ncbi.nlm.nih.gov/pubmed/805209