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Nonallelic behavior of rabbit variable-region allotypes
Group a allotypes not detected by qualitative typing or anticipated from breeding data (latent allotypes) were detected at low levels in 50% of normal rabbit sera tested. The latent allotypes, which were serologically identical to allotypes of pooled IgG, were detected in sera from rabbits with all...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1975
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189849/ https://www.ncbi.nlm.nih.gov/pubmed/1127384 |
| _version_ | 1782146711563534336 |
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| collection | PubMed |
| description | Group a allotypes not detected by qualitative typing or anticipated from breeding data (latent allotypes) were detected at low levels in 50% of normal rabbit sera tested. The latent allotypes, which were serologically identical to allotypes of pooled IgG, were detected in sera from rabbits with all possible combinations of group a allotypes and their occurrence in individual rabbits was transitory and sporadic. These findings give reason to question the assumption that the synthesis of immunoglobulin allotypes is directed by allelic structural genes. |
| format | Text |
| id | pubmed-2189849 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1975 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21898492008-04-17 Nonallelic behavior of rabbit variable-region allotypes J Exp Med Articles Group a allotypes not detected by qualitative typing or anticipated from breeding data (latent allotypes) were detected at low levels in 50% of normal rabbit sera tested. The latent allotypes, which were serologically identical to allotypes of pooled IgG, were detected in sera from rabbits with all possible combinations of group a allotypes and their occurrence in individual rabbits was transitory and sporadic. These findings give reason to question the assumption that the synthesis of immunoglobulin allotypes is directed by allelic structural genes. The Rockefeller University Press 1975-06-01 /pmc/articles/PMC2189849/ /pubmed/1127384 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Articles Nonallelic behavior of rabbit variable-region allotypes |
| title | Nonallelic behavior of rabbit variable-region allotypes |
| title_full | Nonallelic behavior of rabbit variable-region allotypes |
| title_fullStr | Nonallelic behavior of rabbit variable-region allotypes |
| title_full_unstemmed | Nonallelic behavior of rabbit variable-region allotypes |
| title_short | Nonallelic behavior of rabbit variable-region allotypes |
| title_sort | nonallelic behavior of rabbit variable-region allotypes |
| topic | Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189849/ https://www.ncbi.nlm.nih.gov/pubmed/1127384 |