Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo

Peritoneal macrophages from T. cruzi-immune mice were resistant to infection in vitro with culture forms of the parasite. Macrophage resistance appeared in infected mice about 21 days postinfection when parasitemia was still rising. Resistance in vitro was nonspecific since macrophages from BCG-immu...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189902/
https://www.ncbi.nlm.nih.gov/pubmed/806649
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description Peritoneal macrophages from T. cruzi-immune mice were resistant to infection in vitro with culture forms of the parasite. Macrophage resistance appeared in infected mice about 21 days postinfection when parasitemia was still rising. Resistance in vitro was nonspecific since macrophages from BCG-immune mice were resistant to T. cruzi, and since macrophages from T. cruzi-immune mice were resistant to infection in vitro with Listeria were not resistant to challenge with T. cruzi even when the parasites were opsonized.
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spelling pubmed-21899022008-04-17 Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo J Exp Med Articles Peritoneal macrophages from T. cruzi-immune mice were resistant to infection in vitro with culture forms of the parasite. Macrophage resistance appeared in infected mice about 21 days postinfection when parasitemia was still rising. Resistance in vitro was nonspecific since macrophages from BCG-immune mice were resistant to T. cruzi, and since macrophages from T. cruzi-immune mice were resistant to infection in vitro with Listeria were not resistant to challenge with T. cruzi even when the parasites were opsonized. The Rockefeller University Press 1975-08-01 /pmc/articles/PMC2189902/ /pubmed/806649 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo
title Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo
title_full Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo
title_fullStr Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo
title_full_unstemmed Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo
title_short Killing in vitro of Trypanosoma cruzi by macrophages from mice immunized with T. cruzi or BCG, and absence of cross-immunity on challege in vivo
title_sort killing in vitro of trypanosoma cruzi by macrophages from mice immunized with t. cruzi or bcg, and absence of cross-immunity on challege in vivo
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189902/
https://www.ncbi.nlm.nih.gov/pubmed/806649

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